Millennium Science
Enabling next-generation research
- Home
- Instruments
- Reagents
- Applications
- Latest Updates
- Promotions
- Events
- About us
- Contact Us
Roche are excited to bring a new and upgraded target enrichment solution to the market that will enable researchers to achieve higher result confidence with increased sequencing efficiency. The upgraded KAPA Target Enrichment Portfolio combines Roche's renowned design, content and NGS Sample Prep Reagents expertise, to deliver superior capture and sequencing uniformity, fewer PCR duplicates and deeper target coverage through our streamlined and fully automatable Sample Preparation workflow.
A user-friendly online web interface supporting in-silico (probe selection) custom design preparation based on user input regions. It supports both user-directed automatic design preparations or expert designer assisted design preparations.
For whole exome sequencing (WES) solution. It is designed with comprehensive coverage of the latest HG38 human genome build coding regions from CCDS, RefSeq, Ensembl, GENCODE and ClinVar databases, including 387 Sample Tracking SNPs to facilitate sample identity tracking throughout the workflow.
A custom design solution for standard Human probe designs (HyperChoice) and a custom design solution for Non-Human probe designs and Non-Standard Human probe designs (HyperExplore)
The new workflow requires the following reagents and kits: KAPA Universal Adapter, KAPA UDI Primer mixes, KAPA HyperCapture Reagent, KAPA HyperCapture Bead Kit, KAPA Probes Resuspension Buffer and KAPA Hybrid Enhancer Reagent. Check out the new HyperCap workflow Guide.
One of the key factors that drove Roche to improve their Targeted Enrichment Portfolio is the ability to provide researchers with a workflow that they could support from start to finish. i.e. Sample preparation through to library preparation, then target enrichment and then the results. The trusted KAPA brand of library prep reagents can be used seamlessly upfront of capture to provide researchers with a complete workflow.
Already an existing customer and have a NimbleDesign Account? No need to worry, if you had a NimbleDesign account, your previous designs will be transferred to the new HyperDesign Tool, so when you log in you'll still be able to view these. Please note if you want to use the same designs contact us first and we'll discuss the options with you.
Also check out the guide for reviewing and approving designs in HyperDesign here.
New to HyperDesign? If you are new and would like to start on some probe designs, all you need to do is create an account and away you go!
Click here to create your new account.
To help us provide you with the information you need and understand what your requirements are for your project, do let us know the following information:
Hybridization-Based Target Enrichment
Explore the KAPA target enrichment portfolio. KAPA HyperExome Probes cover the CCDS, RefSeq, Ensembl, Gencode and ClinVar genomic databases in an efficient ~43 Mb capture target size. Our custom products: KAPA HyperChoice Probes enable users to design custom human probes with the HyperDesign Tool, while KAPA HyperExplore Probes are for less well-known or complex custom designs pushed beyond normal boundaries.
If you have any questions, would like more information or if you would like to talk to someone please contact sales@mscience.com.au.